{"product_id":"cannanda-cb2-hemp-seed-oil-240ml","title":"Cannanda CB2 Hemp Seed Oil 240ml","description":"\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cspan\u003eCannanda is proud and excited to present one of our greatest innovations: our CB2\u003c\/span\u003e\u003cspan\u003e blend is a legal, non-prescription alternative to cannabidiol (CBD) or used to \u003c\/span\u003e\u003cem\u003eenhance your CBD experience\u003c\/em\u003e\u003cspan\u003e. CBD is the popular cannabis compound that has significant health benefits, but lacks the psychoactive effects of its sister compound, THC. This means you get a number of incredible health benefits without feeling \"high,\" and it delivers these benefits by positively influencing the endocannabinoid system (ECS; the body's master regulator of homeostasis).\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cspan\u003eCannanda's research and development has created our proprietary CB2™ terpene blend, which harnesses the power of terpenes in a very specific blend that promotes the health of the ECS. This unique blend achieves its health-giving benefits through the activation of one of the main receptors of the ECS, a receptor called the cannabinoid receptor type 2 (CB2).\u003c\/span\u003e\u003c\/span\u003e \u003cspan style=\"font-size: medium;\" size=\"3\"\u003eCB2 is one of the two main receptors of the ECS. There are numerous benefits to activating this receptor without activating the CB1 receptor (the receptor THC activates, and is responsible for the \"high\" associated with cannabis). The following is a list of studies illustrating the benefits of CB2 activation.\u003cbr\u003e\u003cbr\u003e\u003cu\u003ePain \u0026amp; Inflammation:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptor and its role as a regulator of inflammation (Cell Mol Life Sci. 2016; 73(23): 4449-70.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eTargeting\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors and the endocannabinoid system for the treatment of pain (Brain Res Rev. 2009 Apr; 60(1): 255-266.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eCannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (Br J Pharmacol. 2008 Jan; 153(2): 319–334.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eAutism Spectrum Disorders:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eEndocannabinoid signalling in autism (Neurotherapeutics. 2015 Oct; 12(4): 837–847.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eEndocannabinoid signal dysregulation in autism spectrum disorders (int J Mol Sci. 2017; 18: 1425.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eDegenerative neurological conditions:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ecannabinoid receptor as potential target against Alzheimer’s Disease (Front Neurosci. 2016; 10: 243.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eTargeting cannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors in the central nervous system. Medicinal chemistry approaches with focus on neurodegenerative disorders (Front Neurosci. 2016; 10: 406.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eCentral\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential (Neural Regen Res. 2016 Sep; 11(9): 1409–1410.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eCannabinoid type 2 (\u003cstrong\u003eCB2\u003c\/strong\u003e) receptors activation protects against oxidative stress and neuroinflammation associated dopaminergic neurodegeneration in rotenone model of Parkinson’s Disease (Front Neurosci. 2016; 10: 321.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson’s disease (Exp Mol Med. 2016 Jan; 48(1): e205.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptor: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies (Br J Pharmacol. 2008 Jan; 153(2): 216–225.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eCannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors in human brain inflammation (Br J Pharmacol. 2008 Jan; 153(2): 277–285.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eOsteoarthritis:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eCannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint (PLoS One. 2013; 8(11): e80440.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eExpression of cannabinoid receptors in human osteoarthritic cartilage: Implications for future therapies (Cannabis Cannabinoid Res. 2016 Jan 1;1(1):3-15)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eRheumatoid arthritis:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eas a potential therapeutic target in rheumatoid arthritis (Musculoskeletal Disorders. 2014; 15: 275.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eImmune system modulation:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003c\/strong\u003e: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eEmerging role of the\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ecannabinoid receptor in immune regulation and therapeutic prospects (Expert Rev Mol Med. 2009 Jan 20; 11: e3.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eCardiovascular:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003edrives neurogenesis and improves functional outcome after stroke (Stroke. 2017 Jan;(48)1:204-212.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eProspects for creation of cardioprotective drugs based on cannabinoid receptor agonists (J Cardiovasc Pharmacol Ther. 2016 May;21(3):262-72.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cstrong\u003eCB2\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein atherosclerosis and acute cardiovascular diseases (Curr Med Chem. 2014;(21)35:4046-58.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cu\u003eMigraine:\u003c\/u\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003eActivation of\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors as a potential therapeutic target for migraine: evaluation in an animal model (J Headache Pain. 2014; 15(1): 14.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cbr\u003eIngredients:\u003c\/strong\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e Organic hemp seed oil, Cannanda’s proprietary CB2 terpene blend.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuggested Use: \u003c\/strong\u003e\u003cspan style=\"font-size: medium;\" size=\"3\"\u003e\u003cspan\u003eTake 1-2 tbs daily with meals. Start with 1\/2 tbs and slowly increase to your preferred dose. Use raw and unheated. Try using as a salad dressing, or blend into smoothies, protein or green drinks, and any other healthy recipe that does not involve heat or cooking, or consume directly off the spoon.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"BeFit.ca","offers":[{"title":"Original Flavour","offer_id":48562651529421,"sku":"BDDF_SKUjl8UcWCqIwFYHDih","price":29.89,"currency_code":"CAD","in_stock":true},{"title":"Natural Orange Creamsicle Flavour","offer_id":48562651562189,"sku":"BDDF_SKUybK6CYNpxTHw7uI0","price":29.89,"currency_code":"CAD","in_stock":true},{"title":"Natural Sweet Ginger Flavour","offer_id":48562651594957,"sku":"BDDF_SKUNVzuHeo8I2UgVjtU","price":29.89,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0577\/8659\/7581\/files\/Cannanda_Original_Flavour.png?v=1778271488","url":"https:\/\/befit.ca\/ur\/products\/cannanda-cb2-hemp-seed-oil-240ml","provider":"BeFit.ca","version":"1.0","type":"link"}