{"product_id":"cannanda-cb2-aromatherapy-wellness-blend-5-ml","title":"Cannanda CB2 Aromatherapy Wellness Blend (5 ml)","description":"\u003cp\u003e\u003cspan size=\"3\"\u003e\u003cspan\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eCannanda\u003c\/strong\u003e\u003c\/span\u003e is proud and excited to present one of our greatest innovations: \u003cstrong\u003eour CB2\u003c\/strong\u003e\u003c\/span\u003e\u003cstrong\u003e™\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e blend is a legal\u003c\/strong\u003e, \u003cstrong\u003enon-prescription alternative to cannabidiol (CBD)\u003c\/strong\u003e or \u003cstrong\u003eused to \u003c\/strong\u003e\u003c\/span\u003e\u003cstrong\u003e\u003cem\u003eenhance your CBD experience\u003c\/em\u003e\u003c\/strong\u003e\u003cspan\u003e. \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan size=\"3\"\u003e\u003cspan\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cstrong\u003eCBD\u003c\/strong\u003e\u003c\/span\u003e \u003cem\u003eis the popular cannabis compound that has significant health benefits\u003c\/em\u003e, \u003cem\u003ebut lacks the psychoactive effects of its sister compound, THC\u003c\/em\u003e. \u003cstrong\u003eThis means you get a number of incredible health benefits without feeling \"high\u003c\/strong\u003e,\" and it delivers these benefits by positively influencing the endocannabinoid system (ECS; the body's master regulator of homeostasis).\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan size=\"3\"\u003eThere are numerous benefits to activating this receptor without activating the CB1 receptor (the receptor THC activates, and is responsible for the \"high\" associated with cannabis). The following is a list of studies illustrating the benefits of CB2 activation.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003e\u003cu\u003ePain \u0026amp; Inflammation:\u003c\/u\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptor and its role as a regulator of inflammation (Cell Mol Life Sci. 2016; 73(23): 4449-70.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eTargeting\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors and the endocannabinoid system for the treatment of pain (Brain Res Rev. 2009 Apr; 60(1): 255-266.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eCannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors: a therapeutic target for the treatment of inflammatory and neuropathic pain (Br J Pharmacol. 2008 Jan; 153(2): 319–334.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eAutism Spectrum Disorders:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eEndocannabinoid signalling in autism (Neurotherapeutics. 2015 Oct; 12(4): 837–847.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eEndocannabinoid signal dysregulation in autism spectrum disorders (int J Mol Sci. 2017; 18: 1425.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eDegenerative neurological conditions:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ecannabinoid receptor as potential target against Alzheimer’s Disease (Front Neurosci. 2016; 10: 243.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eTargeting cannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors in the central nervous system. Medicinal chemistry approaches with focus on neurodegenerative disorders (Front Neurosci. 2016; 10: 406.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eCentral\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential (Neural Regen Res. 2016 Sep; 11(9): 1409–1410.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eCannabinoid type 2 (\u003cstrong\u003eCB2\u003c\/strong\u003e) receptors activation protects against oxidative stress and neuroinflammation associated dopaminergic neurodegeneration in rotenone model of Parkinson’s Disease (Front Neurosci. 2016; 10: 321.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson’s disease (Exp Mol Med. 2016 Jan; 48(1): e205.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptor: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies (Br J Pharmacol. 2008 Jan; 153(2): 216–225.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eCannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors in human brain inflammation (Br J Pharmacol. 2008 Jan; 153(2): 277–285.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eOsteoarthritis:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eCannabinoid\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint (PLoS One. 2013; 8(11): e80440.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eExpression of cannabinoid receptors in human osteoarthritic cartilage: Implications for future therapies (Cannabis Cannabinoid Res. 2016 Jan 1;1(1):3-15)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eRheumatoid arthritis:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003eas a potential therapeutic target in rheumatoid arthritis (Musculoskeletal Disorders. 2014; 15: 275.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eImmune system modulation:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003c\/strong\u003e: Potential role in immunomodulation and neuroinflammation (J Neuroimmune Pharmacol. 2013 Jun; 8(3): 608-620.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eEmerging role of the\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ecannabinoid receptor in immune regulation and therapeutic prospects (Expert Rev Mol Med. 2009 Jan 20; 11: e3.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eCardiovascular:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003edrives neurogenesis and improves functional outcome after stroke (Stroke. 2017 Jan;(48)1:204-212.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eProspects for creation of cardioprotective drugs based on cannabinoid receptor agonists (J Cardiovasc Pharmacol Ther. 2016 May;21(3):262-72.)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003e\u003cstrong\u003eCB2\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein atherosclerosis and acute cardiovascular diseases (Curr Med Chem. 2014;(21)35:4046-58.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan size=\"3\"\u003e\u003cu\u003eMigraine:\u003c\/u\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan size=\"3\"\u003eActivation of\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eCB2\u003cspan\u003e \u003c\/span\u003e\u003c\/strong\u003ereceptors as a potential therapeutic target for migraine: evaluation in an animal model (J Headache Pain. 2014; 15(1): 14.)\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003e\u003cu\u003eRecommended Use\u003c\/u\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan size=\"3\"\u003e\u003cspan\u003e\u003cu\u003eCB2\u003c\/u\u003e\u003cu\u003e™ Wellness Blend\u003c\/u\u003e \u003cstrong\u003e(aromatherapy\/topical)\u003c\/strong\u003e: Best used through direct inhalation (place about 3 drops in your hand, rub hands together, cup around nose\/mouth, and take slow, deep breaths). May be used as a natural flavour (for example, 2-5 drops may be be added to a tablespoon of any edible oil of your choosing), or even used topically for targeted local relief (use a carrier oil). \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"BeFit.ca","offers":[{"title":"Default Title","offer_id":48562651201741,"sku":"BDDF_SKUprenYKrXy0YEWrmN","price":26.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0577\/8659\/7581\/files\/UntitledDesign-2024-03-05T171228.156.png?v=1778271247","url":"https:\/\/befit.ca\/hi\/products\/cannanda-cb2-aromatherapy-wellness-blend-5-ml","provider":"BeFit.ca","version":"1.0","type":"link"}